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Is 'immunotherapy' a cancer game-changer?

09/17/2016

Immunotherapy seeks to expose tumours to the cancer-killing power of the human immune system. It was declared “Breakthrough of the Year” by the journal Science in December 2013.

First Patient Dosed in a Phase I Study of CB-1158

09/16/2016

Arginase is an enzyme in myeloid-derived suppressor cells (MDSCs), which prevents T-cell and natural killer (NK) cell activation in tumors.

FDA Modifies Dosing Regimen for Nivolumab

09/16/2016

The new dosage regimen is for 240mg IV every 2 weeks until disease progression or intolerable toxicity for renal cell carcinoma...

Bi-allelic Alteration and Dysregulation of the Hippo Pathway in Mucinous Tubular and Spindle Cell Carcinoma of the Kidney

09/15/2016

Cell lines (CAKI-1, HK2 or A704) were either transfected with 2 independent siRNAs or non-target controls.

Exelixis, Ipsen say EU approves kidney cancer drug

09/15/2016

The drug, cabometyx, is approved for patients in advanced stages of the disease who have already received prior treatment. The drug was approved by the U.S.'s Food and Drug Administration in April.

Targeted therapy: An elusive cancer target

09/15/2016

Advanced tumors may have met their match with new drugs, but why have these treatments proved ineffective at stopping early-stage tumors from coming back?

Kidney and Thyroid Cancer Rates Up Among U.S. Children, Study Finds

09/12/2016

Siegel hopes that these findings will encourage investigators to find out the "driving forces behind these increases."

What Is Sickle Cell Trait?

09/11/2016

In rare circumstances, a person with sickle cell trait may develop a rare kidney cancer called renal medullary carcinoma.

Body Mass Index and Metastatic Renal Cell Carcinoma: Clinical and Biological Correlations

09/11/2016

High BMI is a prognostic factor for improved survival and progression-free survival in patients with metastatic RCC...

Hereditary leiomyomatosis and renal cell cancer

08/29/2016

Summary of "Hereditary leiomyomatosis and renal cell cancer syndrome: identification and clinical characterization of a novel mutation in the FH gene in a Colombian family."

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