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"To this end, we developed a high-throughput screen to identify small molecules derived from plants, microorganisms, and marine organisms to which CCRCC cells are sensitive. Screening over 8,000 compounds using this approach, we report here the identification of the microbially derived compound carminomycin I (CA) as an effective inhibitor of VHL-defective (VHL(-/-)) CCRCC cell proliferation..."
What is undoubtedly clear is that 10 years ago, as we peered into the crystal ball of targeted therapies, enormous toxicities and questionable outcomes were not what we expected.
AVEO Pharmaceuticals, Inc. (NASDAQ: AVEO) today announced that it has initiated patient enrollment in a multi-center Phase 2 exploratory biomarker study of tivozanib, its lead product candidate designed to optimally block the VEGF pathway by inhibiting all three VEGF receptors, in patients with renal cell carcinoma (RCC).
"I must reluctantly conclude that Congress exceeded the bounds of its authority in passing the act with the individual mandate," the judge said.
Researchers at the National Institutes of Health and the University of Hong Kong have discovered that high levels of a particular protein in cancer cells are a reliable indicator that a cancer will spread.
$50 donation by the bank when you first use the card and ongoing contributions.
In an audacious twist on the concept of fighting fire with fire, scientists have developed a provocative strategy of fighting cancer with cancer.
New Facebook Group chats Tuesday evenings
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