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Investigators target vascular endothelial growth factor

04/15/2010

A new study, 'The relationship of vascular endothelial growth factor and coagulation factor (fibrin and fibrinogen) expression in clear cell renal cell carcinoma,' is now available. In this recently published article, scientists in Amsterdam, Netherlands conducted a study "To investigate the relationship between angiogenesis and coagulation markers in tumor tissues of primary renal cell carcinoma (RCC). Tumors stimulate angiogenesis and activate the coagulation cascade."

Multilocular cystic renal cell carcinoma is a subtype of clear cell renal cell carcinoma

04/15/2010

Multilocular cystic renal cell carcinoma is an uncommon low grade renal cell carcinoma with unique morphologic features. Its cytogenetic characteristics have not been fully investigated.

Neoadjuvant temsirolimus effectiveness in downstaging advanced non-clear cell renal cell carcinoma

04/15/2010

After 6 wk of treatment, a significant downstaging of the disease and complete disappearance of the metastases were noticed on computed tomography scan.

Pfizer Oncology to present cancer drugs at annual cancer research conference

04/15/2010

The company will present data on investigational cancer drugs such as figitumumab, a monoclonal antibody for lung cancer, as well as Sutent (sunitinib) and the kidney cancer drug axitinib, as well as drugs for lymphoma and others.

Green Tea "Promising Agent" in Kidney Cancer

04/15/2010

Green tea may be an effective anticancer agent for renal cell carcinoma(or RCC), the most common type of kidney cancer in adults, and one of the most deadly.

Oncology Investigators Leading Promising Research to be Awarded More Than $7.1 Million at the 2010 ASCO Annual Meeting

04/14/2010

Each of this year’s 46 awardees will receive a 1-year grant of $50,000 to fund his or her investigative studies as they begin their careers in clinical oncology research. The Kidney Cancer Association is pleased to be a collaborator in funding these important grants.

RCC treatment-related hypertension may be marker for efficacy

04/14/2010

A retrospective, exploratory analysis of prospective clinical trials showed treatment-related hypertension was associated with significantly greater progression-free survival and overall survival in patients with metastatic renal cell carcinoma . . .

AVEO Pharmaceuticals' Translational Research Platform and Novel Antibody Pipeline

04/14/2010

Phase 3 clinical trial called TIVO-1 comparing tivozanib to sorafenib in advanced kidney cancer, as well as additional clinical studies in other solid tumor types.

Researchers find proteins to detect kidney cancer

04/14/2010

The researchers identified a pair of proteins -- aquaporin-1, or AQP1, and adipophilin, or ADFP, -- that are excreted in the urine that could lead to earlier and more accurate diagnosis of the disease. The proteins were not elevated in people without cancer.

AACR and Landon Foundation Support the Next Generation of Researchers with the INNOVATOR Awards

04/14/2010

W. Kimryn Rathmell, M.D., Ph.D.'s project, Advancing Prognostic Algorithms for Renal Cell Carcinoma, focuses on renal cell carcinoma, a type of kidney cancer.

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