Large-scale data mining of gene networks in fruit flies has led researchers to a sensitive and specific diagnostic biomarker for human renal cell carcinoma, the most common type of kidney cancer. The biomarker known as SPOP is produced by 99 percent of clear cell renal cell carcinomas but not by normal kidney tissue.
Its lead products - IMA901 for the therapy of renal cell cancer and IMA910 for the treatment of colon cancer - are currently investigated in international phase II clinical studies.
James D. Range - an environmental lawyer and lobbyist who cofounded the Theodore Roosevelt Conservation Partnership - an influential coalition of hunting, fishing, and conservation groups - died of kidney cancer Jan. 20 at the Mayo Clinic in Rochester, Minn.
"I have fourth-stage cancer, and I'm going to die," said Fanning, former assistant manager of a local hotel, holding back tears. "I tell myself if I live I can spend time with my family, but if I die I will be in heaven..."
As Barack Obama closed in on the Presidency last year, investors got increasingly skittish about drug stocks. Johnson & Johnson fell 18% in the two months before the election, Schering-Plough dropped 23%, and Eli Lilly tumbled 28%. Investors had good reason to be worried.
A Wall Street Journal report says a combination of these two U.S. pharmaceutical giants would redraw the boundaries of the global drug industry.
The end result is that only sick people end up paying for health care.
A rumored Pfizer-Wyeth marriage signals big change for the drug business.
President Barack Obama is the first new President to develop a comprehensive cancer plan. While the plan reflects strong emphasis on oncology, disturbingly no reference is made to prevention, and the wide range of avoidable causes of cancer.
The role of laparoscopic radical nephrectomy (LRN) for very large renal tumors remains to be defined. We review our experience with LRN for very large (>/=10 cm) renal malignancies.