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Mundipharma EDO GmbH have entered into an agreement for the development and testing of a DRP™ biomarker for Mundipharma EDO’s lead compound EDO-S101
"We are excited at the prospect of our partner Mundipharma EDO moving into Phase I with a DRP™ biomarker developed by MPI A/S,"
Cancer / Oncology Neurology / Neuroscience Melanoma / Skin Cancer Radiology / Nuclear Medicine Nivolumab combined with radiation therapy may be new treatment option
Nivolumab has been approved by the Food and Drug Administration to treat advanced non-small cell lung cancer, renal cell carcinoma, and melanoma; however, the impact of nivolumab on brain metastases is unclear.
The highest response rates were observed in patients with a high Fuhrman grade or sarcomatoid features (22%), grade 4 tumors (25%), or sarcomatoid histology (33%). Overall, 46% of patients had some degree of tumor shrinkage, the authors reported.
“The news that Eisai has submitted this application is hugely positive, for both clinicians and patients alike. The current outlook for people with this aggressive cancer is poor, and therefore the potential of lenvatinib is very exciting indeed.” - See more at: http://www.onclive.com/web-exclusives/lenvatinib-everolimus-combo-submitted-for-approval-in-advanced-rcc#sthash.nJ74LEgg.dpuf
In a poster presentation entitled “The Anti-Cancer Effects of Supinoxin (RX-5902) in Renal Cell Cancer,” Rexahn scientists detailed the results of several preclinical studies showing the antiproliferative effects of Supinoxin in various human renal cancer cell lines and xenograft renal cancer models.
The number of patients with renal cancer in Europe is estimated to be 115,000,1 and renal cell carcinoma comprises more than 90% of all malignancies of the kidney.2 For advanced or metastatic renal cell carcinoma that is difficult to treat with surgery, the standard treatment method is molecular targeted drug therapy, however with low 5-year survival rates, this remains a disease with significant unmet medical need.
His abstract was recognized as a Top Poster in the track.
Dr. Toni Choueiri, of Dana Farber, presents highlights from ASCO GU 2016 Genitourinary Symposium held in San Francisco
The number of new cancer diagnoses in the U.S. is largely steady while the number of cancer deaths continues to decline, according to a new report from the nation's leading cancer advocacy group.
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