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When I was diagnosed with kidney cancer a few years ago, my husband called all our medical connections and asked for the name of the best doctor in that field.
Targeted therapies have improved clinical outcomes over the past several years for patients with advanced renal cell cancer.
The medicines represent many cutting-edge approaches, including one medicine that targets and kills specific cancer cells, and then activates the patient's immune system to destroy any remaining cancer.
We investigated whether germline mutations in fumarate hydratase (FH) or succinate dehydrogenase subunit genes (SDHB, SDHC, SDHD) were associated with RCC susceptibility.
The National Health Service drugs rationing body has been forced to review its policy of banning life-prolonging cancer medicines that are available elsewhere in Europe.
A coach load of campaigners from the county met Andrew Dillon, chief executive of the National Institute for Clinical Excellence, the organisation that licenses drugs for use on the NHS.
The availability of kidneys for transplantation could be increased by using kidneys removed for small, incidentally detected tumors, the results of an Australian study suggest.
He said draft guidance issued by the National Institute for Health and Clinical Excellence (Nice) to deny patients four kidney cancer drugs on the NHS was a "disgrace".
"Based on Lenocta's demonstrated anti-tumor activity against melanoma, renal cancer, prostate cancer, leukemia, and other cancers both alone and in combination with other approved immune-activation agents, including IL-2 and interferons, we believe this product candidate represents a promising approach to treating cancer,"
SF1126, Semafore's PI3 Kinase Inhibitor, Found to Block Angiogenic Signaling From Both VEGF and Bv8 in Multiple Cell Lines
In vitro inhibition of the PI3K/AKT/mTOR pathway by SF1126 was demonstrated to impede the ability of angiogenic stimulants VEGF and Bv8 to activate AKT in a dose dependant manner in two cancer cell lines (786-0 -- renal cell and PC3 prostate).
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