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While the guidance is only in its draft stage, the decision could mean that Eisai’s Kisplyx (lenvatinib) and Eusa Pharma’s Fotivda (tivozanib) are withheld from NHS patients in England and Wales.
This patent provides intellectual property protection for the ongoing human trial that evaluates the effect of the combination of GR-MD-02 with approved cancer immunotherapy drugs
In an interview with OncLive during ASCO, the study’s lead author, Toni Choueiri, MD, senior physician and director of the Kidney Cancer Center at Dana-Farber Cancer Institute, reflected on the avelumab/axitinib results and other emerging combos in RCC.
This educational event will discuss some of the most pressing issues faced by oncologists and other medical experts when dealing with genitourinary malignancies. The summit will discuss critical topics such as bone targeting, treatment of castration-resistant metastatic prostate cancer, kidney cancer and new clinical trials.
Effective July 1, 2017, as part of the settlement the companies entered into an amendment (the “Amendment”) to the existing Collaboration Agreement, dated December 22, 2006, to revise the revenue and cost-sharing arrangements for the collaboration. The Amendment resolves the companies’ dispute pursuant to the arbitration demand filed on June 3, 2016, and aligns both companies’ interests in advancing cobimetinib as a promising therapy for patients with multiple forms of cancer.
Kidney Cancer is an international multidisciplinary journal to facilitate progress in understanding the epidemiology/etiology, genetics, molecular correlates, pathogenesis, pharmacology, ethics, patient advocacy and survivorship, diagnosis and treatment of tumors of the kidney.
"To make progress we need to look at investing more money to hasten the implementation of the Cancer Strategy; we need to speed up, not slow down, patient access to cost-effective medicines in the NHS and we need to create a more ambitious plan for using real-world evidence to shine a light on cancer treatment outcomes."
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A drug which could prolong life for people with advanced kidney cancer has been approved for use on the NHS in England and Wales.
The European Medicines Agency's Committee for Medicinal Products for Human Use (CHMP) has adopted a positive opinion recommending the approval of FOTIVDA® (tivozanib) for the management of adult patients with advanced renal cell carcinoma (RCC). EUSA's marketing authorisation application included data from the TiVO-1 pivotal study, which included over 500 patients with advanced RCC.
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