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Cancer / Oncology Neurology / Neuroscience Melanoma / Skin Cancer Radiology / Nuclear Medicine Nivolumab combined with radiation therapy may be new treatment option
01/28/2016
Nivolumab has been approved by the Food and Drug Administration to treat advanced non-small cell lung cancer, renal cell carcinoma, and melanoma; however, the impact of nivolumab on brain metastases is unclear.
PD-L1 Inhibitor Active in Advanced Kidney Cancer
01/18/2016
The highest response rates were observed in patients with a high Fuhrman grade or sarcomatoid features (22%), grade 4 tumors (25%), or sarcomatoid histology (33%). Overall, 46% of patients had some degree of tumor shrinkage, the authors reported.
Lenvatinib/Everolimus Combo Submitted for Approval
01/17/2016
“The news that Eisai has submitted this application is hugely positive, for both clinicians and patients alike. The current outlook for people with this aggressive cancer is poor, and therefore the potential of lenvatinib is very exciting indeed.” - See more at: http://www.onclive.com/web-exclusives/lenvatinib-everolimus-combo-submitted-for-approval-in-advanced-rcc#sthash.nJ74LEgg.dpuf
Supinoxin™ Oral Administration Produces Clinically Meaningful Tumor Inhibition
01/13/2016
In a poster presentation entitled “The Anti-Cancer Effects of Supinoxin (RX-5902) in Renal Cell Cancer,” Rexahn scientists detailed the results of several preclinical studies showing the antiproliferative effects of Supinoxin in various human renal cancer cell lines and xenograft renal cancer models.
Eisai submits EMA application of in-house developed lenvatinib for renal cell carcinoma
01/12/2016
The number of patients with renal cancer in Europe is estimated to be 115,000,1 and renal cell carcinoma comprises more than 90% of all malignancies of the kidney.2 For advanced or metastatic renal cell carcinoma that is difficult to treat with surgery, the standard treatment method is molecular targeted drug therapy, however with low 5-year survival rates, this remains a disease with significant unmet medical need.
Ilya Tsimafeyeu receives prestigious ASCO Merit Award
01/11/2016
His abstract was recognized as a Top Poster in the track.
Kidney Cancer Highlights From GU ASCO
01/10/2016
Dr. Toni Choueiri, of Dana Farber, presents highlights from ASCO GU 2016 Genitourinary Symposium held in San Francisco
Discontinuing VEGF-targeted therapy for progression or toxicity affects outcomes of second-line therapies in mRCC
01/09/2016
Dr de Velasco talks to ecancertv at ASCO GU 2016 about analysing when VEGF-targeted therapy for metastatic renal cell carcinoma (mRCC) is discontinued.
New U.S. cancer cases holding steady, deaths declining
01/09/2016
The number of new cancer diagnoses in the U.S. is largely steady while the number of cancer deaths continues to decline, according to a new report from the nation's leading cancer advocacy group.
FDA to Review Expanded Indication for Cabozantinib
01/04/2016
Exelixis announced that it has completed the submission of its rolling New Drug Application (NDA) with the Food and Drug Administration (FDA) and requested Priority Review for cabozantinib (tablet formulation) as a treatment for patients with advanced renal cell carcinoma (RCC) who have received one prior therapy.
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