News Posts List
British Scientists Identify Kidney Cancer's Cellular Origin
08/10/2018
Researchers from Wellcome Sanger Institute, the University of Cambridge and the University of Newcastle discovered that adult renal carcinoma cells are a version of a specific rare subtype of healthy adult kidney cell, called PT1. They found that despite genetic differences, all the renal carcinoma cells studied had developed the same PT1 characteristics. These results could provide the basis of a new method for treating cancer by targeting the PT1 cell specifically.
Renal Cell Carcinoma and Myelodysplastic Syndrome Show Epigenetic Association
08/09/2018
Hypermethylation has been documented in some myeloid disorders including myelodysplastic syndrome (MDS) and in renal cell carcinoma (RCC). A group at the Mayo Clinic noticed the epigenetic marking patterns between these vastly different conditions and wondered if there was a connection. The group found that there was a strong association.
Asheville Firefighter's Line-Of-Duty Death Could Set Precedent For Death Benefits
08/09/2018
Asheville firefighter Will Willis died of kidney cancer earlier this year. The Asheville Citizen-Times first reported that for just the second time in such cases, the North Carolina Industrial Commission decided it was a line-of-duty death.
Sunitinib vs Nephrectomy Followed By Sunitinib In Metastatic Renal Cell Carcinoma
08/08/2018
In an interim analysis of the French phase III noninferiority Carmena trial reported in The New England Journal of Medicine, Méjean et al found that sunitinib alone was not inferior in overall survival vs nephrectomy followed by sunitinib in patients with intermediate- or poor-risk metastatic clear cell renal cell carcinoma.
VEGF TKI + Immunotherapy Combinations For mRCC
08/08/2018
This video discusses strategies for metastatic renal cell carcinoma that involve I-O therapies in combination with VEGF-targeted therapies.
Biomarkers May Predict TKI Response In Metastatic RCC
08/08/2018
Angiogenesis-related biomarkers regulated by hypoxia were found to be strong predictors of primary renal tumor response (PRT), progression-free survival (PFS), and overall survival (OS) in patients with metastatic renal cell carcinoma (mRCC) who were being treated with sunitinib prior to kidney removal, according to research published in Clinical Cancer Research.1
Results From The Carmena Trial
08/08/2018
Arnaud Méjean, MD, PhD, of the Hôpital Européen Georges Pompidou, discusses his study’s potentially practice-changing finding that nephrectomy is no longer the standard of care for patients with metastatic renal cell carcinoma (Abstract LBA3).
Dr. Drake On The Role of Cytoreductive Nephrectomy In RCC
08/08/2018
Charles G. Drake, MD, PhD, director of Genitourinary Oncology, NewYork-Presbyterian/Columbia University Medical Center and co-director of Columbia’s Cancer Immunotherapy Programs, discusses the role of cytoreductive nephrectomy in the treatment of patients with renal cell carcinoma (RCC).
New Evidence May Help Improve Management Of Rare Kidney Cancers
08/08/2018
Researchers have identified relapse patterns of nonclear cell renal cell carcinomas — an understudied group of rare kidney cancers — that are distinct from the more common clear cell renal cell carcinomas. The findings may help improve the management of patients with nonclear cell renal cell carcinomas (non-ccRCC), who represent approximately 20 percent of kidney cancer patient populations.
How Ablation Destroys Cancer To Prolong Lives
08/07/2018
Ablation is a minimally invasive procedure that uses targeted radiation to kill tumors. This technique is prolonging survival rates for kidney cancer patients.
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